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Pharmaceutical / Medical Biotech / Biotech Industry

Drug Development

In the process of drug development, it is very important to ensure the effectiveness and safety of products before they reach the consumers. To facilitate this, TCELS is constantly engaged in projects that support infrastructure development for pre-clinical testing and clinical research. TCELS also promotes regulatory compliance. Thai Pharmaceutical Manufacturers Association (TPMA) is a key collaborator of TCELS.

Our drug development programme includes:

1. Pre-clinical Testing

a. Health Products Safety Testing Center

b. Laboratory Animal Breeding Center

c. Laboratory Animal Monitoring Center

2. Clinical Research

3.  Regulatory Compliance

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Drug Discovery / New Generic

 
      TCELS encourages the discovery of new drugs and development of new generics. Along with the Faculty of Pharmaceuticals of Chulalongkorn University, TCELS will be supporting four new generic drugs this year. Growth Hormone project of TCELS, in partnership with KMUTT, is in the pilot plant stage. It is soon expected to move to the stage of pre-clinical trials. TCELS is also supporting the Drugs Discovery Project related to cancer, in partnership with the Prince of Songkla University, Hat Yai. Quebracchitol, a biochemical product obtained from the natural rubber latex serum, is a compound being studied for the treatment of cancer and diseases related to fungal infections of the mouth. 

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Center for Cell & Gene Therapy

TCELS has been involved in cell and gene therapy projects since 2007. To help patients awaiting a bone marrow transplant receive stem cell treatment, TCELS has been working with the Thai Red Cross Society and relevant hospitals towards establishing a national stem cell collection center. Data from this research will also be used to develop future stem cell projects. Currently there is a national center for storage of cord blood for patients requiring a bone marrow transplant that meets international standards.

As announced by the Ministry of Science and Technology in line with the country strategy, in 2013, a Cell and Gene Therapy Center will be established within TCELS. Developing infrastructure for cell and gene therapies will be the main activity of this center.  A GLP laboratory will also be established to develop technologies to cure thalassemia and leukemia patients. Along with this, another laboratory will be established for developing safe and high quality GMP products for therapeutic use and research.

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Medical Devices / Bio Medical Robotic

Advanced Dental Technology Center

Advanced Dental Technology Center (ADTEC) was initiated in 2012. Projects of ADTEC include design and development of dental implant and materials for improving the quality of patients’ lives. Some of these projects are:

  • Design, development and manufacturing of dental implants.
  • Design and development of craniofacial implants for facial prostheses.
  • Design and development of mini-implant for orthodontic.
  • Design and development of mini plates and screws for craniomaxillofacial surgery.
  • Design and development of bone plates and screws for small animals...

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Center for Advanced Medical Robotics

Medical robotics has played an increasingly important role in healthcare as it has clear potential for improving diagnostic and therapeutic capabilities, lowering the number of medical errors and improving the overall quality and cost effectiveness of our health care delivery system. It has been predicted that in 2025, the size of the robot market will reach $66.4 billion. In particular, almost 80% of the market will be accounted for by personal and service robots whose market size will be three times compared to that in 2010. (Source: The Japan Robotics Association)

       The advancement in medical robotics is critical for improving the country's competitiveness. As a result, Thailand Center of Excellence for Life Sciences (Public Organization), Ministry of Science and Technology, has established the advanced medical robotics program, under the flagship policy of the Ministry of Science and Technology, to improve the strength and competitiveness of the country both economically and socially.

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Medical Device Cluster

Following the industrial development guidelines of Thailand, TCELS launched a plan to develop medical device cluster in 2009. In collaboration with the Engineering Faculty of Mahidol University, feasibility study was conducted and a roadmap was designed for the establishment of this medical device cluster.

This roadmap includes the development of medical devices in three areas: medical devices for the market, software-dependent medical devices and medical devices that use advanced technologies.

Major components of the roadmap for Medical Device Cluster project are as follows:

  • A globally strong and competitive medical devices industry will be developed in Thailand.
  • There are greater opportunities for those medical equipment and devices that are useful for the general public....

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Herbal / Cosmeceutical Industry

Skin Whitening Cream

With the support of TCELS, a team of researchers from the Prince of Songkla University, Hat Yai, have developed a product for skin whitening from active ingredients contained in rubber latex. Thailand leads the world in natural rubber production. This project is going to provide an excellent mechanism to create additional value for Thai economy in the long run. The team of researchers discovered four biochemical products from natural rubber latex. One of these products, Hb extract, is used to develop a skin whitening cream. It has already been patented in two countries and is generating revenue. Process for patenting it in other countries is underway. Because of its herbal properties, this skin whitening product is gaining popularity.

 

Thai Traditional Medicine

In collaboration with Naresuan University, TCELS is supporting the clinical research for traditional Thai medicine and herbal products. A feasibility study on the GMP pilot plant for herbal products has already been done.

Medical Services

Personalized Medicine

Pharmacogenomics is the study of human genetics in relation to individuals’ different responses to drugs. This helps in prescribing personalized medicine and reducing allergies and side effects due to use of the wrong medicine. Pharmacogenomics is a powerful tool for drug selection for individual patients so as to reduce the chance of unwanted side effects and the failure of treatment. A reduction in drug side effects can also bring down the cost of treatment. This is particularly beneficial for developing countries with limited resources like Thailand. TCELS is supporting the Pharmacogenomics Project of Ramathibodi Hospital, Mahidol University. 

Under the Pharmacogenomics project, research is also being carried out on the five key diseases that threaten the health of Thais: thalassemia, diseases of the cardiovascular system, AIDS, leukemia in children and dihydropyrimidine dehydrogenase disease (DPD).

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Medicopolis

Medicopolis: Land of Innovative Health Services

TCELS has initiated this ambitious project to transform Thailand into a medicopolis – the medical hub of ASEAN region. In Thailand, healthcare and medical facilities are of international standards. Medical tourism has become a prevalent business model and has given new wings to Thai economy. These developments have brought about a surge in the number of hospitals vying for local and international accreditations and certifications. Many hospitals have obtained the US standard accreditation from the Joint Commission International Accreditation (JCIA) and gained the status of international hospitals.

Along with the modern medical infrastructure and facilities, Thai traditional medicines and therapies are also world renowned. Medicopolis project of TCELS will support the research and development of products and services related to these systems and will promote Thailand as the medical center of the ASEAN region...

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APEC Life Sciences Innovation Forum

Asia Pacific Economic Cooperation (APEC) Life Sciences Innovation Forum (LSIF) was established in 2002. It has since grown to become APEC's leading initiative on health and health sciences innovation. 

It is a tripartite forum that meets annually and engages representatives from the highest levels of government, industry and academia to create the right policy environment for life sciences innovation. The LSIF brings together scientific, health, trade, economic and financial considerations to address the challenges of infectious and chronic disease and ageing populations. 

As the focal point of life sciences industry in Thailand, TCELS has played the lead role in linking both the public and private sectors to mobilize experts to join APEC LSIF and share relevant.....

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